Similar(60)
We measured PER staining intensities - and sub-cellular distributions - and conclude the molecular oscillator in those pacemakers is not simply phase-altered, but instead severely deranged.
To test the efficacy of FAK inhibition in KRAS mutant NSCLC with distinct mutation cohorts (A: TP53, CDKN2A wild type, B: TP53 wild type, CDKN2A altered, C: TP53 mutant, CDKN2A wild type, and D: TP53 mutant, CDKN2A altered), a phase II multi-center study is currently underway in patients with KRAS mutant NSCLC who have already received one platinum doublet regimen.
As this study shows that the genetic signature of the breast epithelium of women taking hormonal contraception resembles that of a continuous luteal phase, the altered regulation of these gene sets could also provide a potential mechanism to account for the increased breast cancer risk associated with progestin-containing oral contraception [ 6].
It is a phase.
Sidebars: Just a Phase?
I had "a phase".
His meanderings are a hint of the strange phases and altered states of L'Avventura.
In stressed conditions, cells gradually enter a growth-arrested state (stationary phase) with altered cell size and heterogeneous transcriptional reprogramming.
In agreement with our studies, this indicates that an altered phase of entrainment is sufficient to drive pathology, and highlights a particular vulnerability of the cardiovascular system.
To establish an altered phase relationship between the environmental LD cycle and the internal circadian clock, male C57Bl/6J mice were placed under 20 h, 22.5 h, 24 h, 27 h and 30 h symmetrical LD cycles for 17 week (from 8 week of age, n > 8/group).
First, there is an altered phase in PER staining intensity measured in the nuclear domain, with the peak at ZT11 for both the 5th s-LNv and ITP- LNd (Figure 6B, 6D).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com