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Therefore, the persistent activation of CA1 pyramidal α7* nAChRs in the presence of 10 µM choline plus 2 µM PNU-120596 would be expected to result in a persistent influx of Ca2+ ions at a rate of ∼0.016 pA (i.e., 10% of 0.16 pA).
Interestingly, the window current determined by the overlap of the steady-state activation and inactivation curves of the Nav1.2 isoform is expected to generate a persistent influx of Na+ between the activation threshold (between −60 mV and −50 mV) and −40 mV [35], [36].
Similar(54)
A most significant observation was a persistent large influx of Cl−, which had a time course similar to the net wound electric currents we have measured previously.
The persistent influx of job seekers contributed to the higher unemployment rate in the city, he said.
These neuroprotective regimes tested in EAE suggest that one of the major mechanisms involved in axonal degeneration during neuroinflammatory diseases, is the persistent influx of Na+ into the axon ultimately leading to neurotoxic levels of Ca2+ (for review see [ 86]).
A persistent accumulation of autophagosomes, concurring to the injury-induced axonal degradation and secondary to the lesion-induced calcium influx, was reported in the optic nerve following optic nerve crush.
A persistent Djokovic.
"A persistent muddler.
A persistent person, too.
It's a persistent thing.
Multitasking is a persistent myth.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com