The phrase "a persistent binding of" is correct and usable in written English.
It can be used in contexts related to programming, data management, or any situation where a continuous connection or association is being described.
Example: "The application experienced a persistent binding of the user session to the database, causing delays in response time."
Alternatives: "a continuous link of" or "an ongoing connection of".
The midbody itself represents the last connection between the dividing cells, and KIF14 had been detected in this structure as well (Carleton et al, 2006; Gruneberg et al, 2006), possibly as a consequence of a persistent binding to the overlapping central microtubules.
We therefore propose that, while persistent DNA damage-induced Tel1 activation is certainly a key feature of sae2∆ cells, it is persistent binding of the MRX complex to nascent 3′ terminal DNA that causes toxicity in sae2∆ cells, likely through it delaying downstream HR events.
DDB1 knockdown led to a significant decrease in nuclear CSA-GFP levels, while CSA-GFP levels in the cytoplasm increased (Fig. 4e), likely due to persistent binding of CSA-GFP to TRiC (Fig. 4a).
Furthermore, we found that in CSA-deficient patient cells expressing CSA 8M RRS was reduced when compared to that in cells expressing CSA WT (Fig. 6b), showing that not only CSA instability, but also persistent binding of CSA to TRiC negatively impacts TC-NER.
The source of the persistent binding of BLM by the third hairpin DNA was identified.
GusA activity was also detected and slightly decreased after 12 h of incubation, which might be explained by the stability of the GusA protein in C. cellulolyticum cells or the persistent binding of intracellular L-arabinose with AraR.
As no free αB-crystallin remained in solution, inhibition must have resulted from the persistent binding of the chaperone to fibrils, providing strong support for the solution-state inhibition results presented previously in Fig. 2.
It does not produce persistent binding of the mu receptor, which would prevent the action of other opioids in acute and chronic painful conditions (Walsh et al 1995); as a result other opioids can be used for breakthrough pain in the presence of buprenorphine (Budd and Collett 2003).
The E38K mutation results in faster and more persistent binding of RecA protein to DNA, and the deletion of 17 amino acid residues from the RecA C-terminus eliminates a flap that negatively autoregulates many RecA activities (Lavery and Kowalczykowski, 1992; Eggler et al., 2003).
Studies performed by Nagai et al. (2006) suggest that dioxin-like compounds that cause the AhR to be permanently active lead to toxic effects, whereas dietary components that promote temporal activation, without persistent binding of the AhR/AhR nuclear translocator complex to dioxin response element sequences, might avoid toxic effects while promoting beneficial effects.
