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Second Saturday, like Beacon, seems to hang its hat on the idea that art, as muse, recreation, status signifier and economic development strategy is one of the few things that have a permanent growth market.
Although the size of cultivated and settlement land covers were initially insignificant, our results showed a permanent growth during the study period (Table 2).
Starbucks needs to go on a permanent growth diet (at least in the U.S ., and realize that it has the metabolism of a 37-year-old and can digest fewer new stores.
In non-hematopoietic cells such as primary fibroblasts, oncogenic RAS induces a permanent growth arrest termed senescence, which limits RAS-induced tumorigenesis in vivo [19] [23].
The progressive shortening of telomeres – repetitive DNA sequences at the ends of the chromosomes – with each cell division ultimately leads to replicative senescence, characterized by a permanent growth arrest [1], [2].
In normal human diploid cells, oncogene activation causes a permanent growth arrest with features of cellular senescence [ 26].
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These may lead to a permanent increase in the growth rate of GDP per capita of a country.
In such conditions, RB-proficient cells establish a seemingly permanent growth arrest that is indicative of cellular senescence.
The p16INK4a-Rb tumour suppressor pathway is required for the initiation and maintenance of cellular senescence, a state of permanent growth arrest that acts as a natural barrier against cancer progression.
Senescence was first described by Hayflick and Moorhead in 1961 when it was noted that fibroblasts entered a state of permanent growth arrest following serial cultivation; a fate that was not shared by cancer cells [ 57].
Once a critical shortened telomere length is attained, it triggers a state of permanent growth arrest called replicative senescence (Harley et al., 1992).
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