The phrase "a permanent alteration" is correct and usable in written English.
It can be used when discussing a change that is intended to last indefinitely or cannot be reversed.
Example: "The renovation resulted in a permanent alteration to the building's structure, making it more accessible."
Alternatives: "a lasting change" or "an irreversible modification".
Therefore, an environmental factor that altered sexual selection was found to promote a permanent alteration in the sperm epigenome in an imprinted-like manner that was inherited for multiple generations (Crews et al. 2007; Skinner et al. 2010).
"Once the homes and the old trees are gone, then that's a permanent alteration to the community".
The loan modification extended by Chase Home Finance was technically a trial, not a permanent alteration, but this fact seemed of lesser significance.
Just as the circumstances of life and the manifestations of crime are changing with time, there is a permanent alteration regarding the issues of medical criminalistics.
This is undoubtedly the case – but then all human activities impact upon the individual brain as they're happening; this by no means implies a permanent alteration, let alone a heritable one.
Thus selective cryosurgery in the AV nodal region produces a permanent alteration in AV conduction.
While this may not be identical to the classical concepts of community stability (but see [5]), it is related to it by representing a quite permanent alteration of community properties and possibly entailing shifts in ecosystem services when lost species are not replaced by functionally equivalent ones.
The efficient and permanent alteration of a human gene responsible for SCID provides a proof-of-principle demonstration of the potential of zinc-finger nucleases as human therapeutics.
Molecular chaperones are proteins which can modulate the folding of a variety of other polypeptides without permanent alteration to themselves [3].
However, the formation of a surfactant double layer cannot be regarded as a permanent wettability alteration of the calcite, because due to the weak hydrophobic bond between the surfactant and the hydrophobic surface, the process is entirely reversible.
In the event the germ line has a permanent epigenetic alteration, a transgenerational epigenetic phenotype may be transmitted [1].
