Sentence examples for a perfect linkage from inspiring English sources

This revealed a perfect linkage between plants with an overexpression phenotype having a high ectopic gene expression in leaves, while plants with an ag mutant phenotype (pARC276), showed no expression.

Similarly, a GWAS of urinary metabolite ratios identified a polymorphism in perfect linkage disequilibrium with rs1495741 to be associated with formate:succinate levels (P=5.1×10−16).

The vast majority of thelytokous females from all three morphotypes were homozygous for a single allele at this locus (allele 183), consistent with a previous study reporting perfect linkage of this allele to a recessive, thelytoky-inducing genetic factor in Lfa [ 17].

For each marker in the interaction for the formamide phenotype, there is a corresponding marker in near perfect linkage in the interaction for the indoleacetic acid phenotype.

This score provides an estimate of disease association by using the linkage disequilibrium score (range 0 to 1, where 1 is perfect linkage disequilibrium) as a weighting for the p-value for a given SNP.

The risk allele T of rs2516448 is in perfect linkage disequilibrium with a frameshift mutation (A5.1) in MICA exon 5, which results in a truncated protein.

60, 61 Interestingly the lead SNP in IRGM (rs13361189) identified in CD is in perfect linkage disequilibrium with a 20 kb deletion upstream to the IRGM locus, 59 hence the risk haplotype includes both deletion and SNP.

Brest et al 62 demonstrated that rs13361189 and the deletion are in perfect linkage disequilibrium with a synonymous exonic SNP (rs10065172) that alters IRGM levels and the binding of microRNA196.

The next most statistically strong association in the region is modest (P = 1.99 × 10−4) and observed at an SNP (rs2294956) which is in perfect linkage disequilibrium with rs12689384 (r= 1, D' = 1) based on HapMap CEU, on which imputation was based.

Perfect linkage was nevertheless found between a kanamycin resistance marker and the mutant phenotype (0 EMB/EMB plants among 204 resistant transplants screened), consistent with T-DNA tagging [4].

Protective haplotypes were in perfect linkage (r = 1.0) with a nonsynonymous coding variant (rs8103142).