Sentence examples for a pattern of modification from inspiring English sources

The genome is epigenetically programmed by changes in the chromatin state and by a pattern of modification of the DNA molecule itself through methylation [17].

For example, the KD of CREBBP decreased from 733 μM for H3K14ac to 131 μM for H3pS10K14acK18ac suggesting that many BRDs recognize a pattern of modifications rather than a single Kac mark.

In addition to inheriting genes, offspring also inherit a pattern of chemical modifications to the DNA of certain genes.

Centromeric chromatin is also characterized by a pattern of histone modifications that is different from that of the flanking heterochromatin [23].

Our analysis of the centromere chromatin of the alphoidtetO HAC in human cells reveals, in addition to the kinetochore histone CENP-A, a pattern of histone modifications diagnostic of that found in the body of many actively transcribed genes (Schneider et al, 2004; Vakoc et al, 2006; Barski et al, 2007; Mikkelsen et al, 2007).

The cataloged information is used to build look-up tables that associate a particular molecular substructure with a specific pattern of modification or conjugation.

ergaster specimens reveal a pattern of descent with modification.

The HAC centromere also displayed a pattern of histone H3 modifications characteristic of the downstream open reading frames of actively transcribed genes and non-coding RNAs (Schneider et al, 2004; Vakoc et al, 2006; Barski et al, 2007; Guttman et al, 2009; Filion et al, 2010).

Moreover, these three parameters are closely related to a pattern of watermarking images so any modification of one of these factors influences directly the others.

This study for the first time demonstrated the molecular size (10 kDa) and pattern of modification (reducing end modification) for BG34-10 to mediate macrophage internalization.

The Cdx2 promoter, active in the trophectoderm and silent in the ICM, shows the opposite pattern of modification, consistent with its transcriptional status (Fig. 2).