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Epigenetic differences between ethnicities are an important consideration when investigating autoimmune disorders with a pattern of heterogeneous risk.
Klintworth et al. evaluated strain pattern distribution on qualitative RTE for 57 parotid tumours (8 malignancies) and documented that a pattern of heterogeneous reticular distribution was more frequent in malignant tumours (38%) than in benign tumours (4%).
Idiopathic pulmonary fibrosis (IPF), by far the most common form of IIP, is histopathologically defined by the presence of the prototypical form of pulmonary fibrosis, usual interstitial pneumonia (UIP), a fibrosing interstitial pneumonia characterized by a pattern of heterogeneous, subpleural regions of fibrotic, and remodeled lung that often results in death within 2 3 years of diagnosis [ 4].
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Yamashita et al. [ 18] observed a similar pattern of heterogeneous populations with increasing doses of antigenic stimulant in the presence of an intermediate level of IL-4.
The mosaic subclinical melanoderma (MSM), also called faint mosaic melanoderma (FMM), is a physiologic pattern of heterogeneous distribution of melanin inside the epidermis.
We observed a striking overall pattern of heterogeneous parental origins, consistent with Druze oral tradition, together with both a high frequency and a high diversity of the mitochondrial DNA (mtDNA) X haplogroup within a confined regional subpopulation.
Display a pattern of leadership.
Identify a pattern of bossiness.
Make a pattern of cat.
Reports of genomic divergence across sister species that diverged ecologically show a consistent pattern of highly heterogeneous genomes (e.g. [ 49- 52]).
Approaches relying on DNA sequence polymorphism to identify individual patterns from a mixture of heterogeneous epigenomes are insufficient as methylcytosines occur at a much higher density than SNPs.
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