Sentence examples for a pathway of action from inspiring English sources

We utilised a pathway of action to understand the working of communication technologies in the diabetes healthcare context [ 15] coupled with several forms of communication technologies [ 18, 19] or other self-management interventions [ 20].

Although many in vitro and in vivo studies have shown that several types of K+ channels are involved in the pathology of depression and even act as a pathway of pharmacological action of some antidepressants, it is still in short of direct evidence about the expression of these potassium channels in depression animal models and in depression patients.

Following the identification of a common pathway of action of ASA/SA and BoxA, we tested the efficacy of BoxA in vivo.

In Locusta migratoria, pathways carrying signals from the DCMD as well as acoustic signals are both shown to synapse onto interneuron 724, which possibly indicates a similar pathway of action for the sound stimulus (Baader, 1991).

Intriguingly, a recent report describes that the transcriptional changes induced by the BET inhibitor I-BET-151 and TG101209 in human erythroleukemic HEL cells are significantly overlapping, and it was concluded that these inhibitors have a common pathway of action.

Although in this case, a chemogenomic approach did not identify the direct binding target of the small molecule, it enabled identification of a pathway of importance to the mechanism of action of the drug.

Although each identified pathway of action contributed to the desired outcomes, a consumer driven recovery was most closely aligned with understanding and utilizing natural supports and acting to reduce the stigma of mental illness.

In stage 2, the actual pathway of action remains unknown [19].

Our findings indicate that these effects may be the result of simultaneous inhibition of JAK2 and BETs by TG101209 (dual pathway of action).

First, the expression readout may be far downstream of the actual binding target and may lead to the pathway of action but not the direct protein target of the molecule.

The concentrations at which XEs are believed to be mechanistically active have largely been determined by assaying for the transcriptional activity of these compounds via the well-established nuclear pathway of action for steroids.