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A key conceptual limitation to this approach is that miRNAs typically target hundreds of transcripts and are more likely to have a profound impact on a pathway like the HR repair pathway by regulating several HR factors.
He created the Beastmen, commanding them to forever fight the people of Vana'diel and occupy their minds, so these children would never have time to group together and construct a pathway like the ones before them.
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A pathway-like visualization can be created using the Cerebral plugin layout.
The network can be switched to a pathway-like view (Fig. 1d), displaying the cellular location of genes.
Based on this information, a pathway-like view can be created using the Cerebral plugin layout (Barsky et al., 2007).
We also earlier demonstrated that somatic mutations in a glioblastoma cancer genome produced a pathway-like pattern of enriched connectivity in the gene interaction network.
We are given one or a few members of a pathway, and would like to infer the other, functionally linked members of the same pathway.
For C. elegans, the genetic and molecular genetic control of the commitment to develop as dauer larvae is well characterised and includes a TGF-β-like pathway, an insulin-like pathway and a guanyl cyclase pathway [ 13].
There has been extensive investigation into the genetic and molecular genetic control of the development of dauer larvae, which is known to be controlled by a TGF-β-like pathway, an insulin-like pathway and a guanyl cyclase pathway [ 1, 2].
A network representation of a signaling pathway, like the one in Fig. 1, can be converted into a discrete dynamic network model by assigning a state variable σi and a regulatory function fi to each node i.
However, if there is an indication showing that A, B, and C, form a linear pathway like the previous case, it becomes immediately clear that there is some inconsistencies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com