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The phrase "a particularly problematic issue" is correct and usable in written English.
It can be used when discussing a specific issue that is notably difficult or troublesome in a given context.
Example: "The committee is facing a particularly problematic issue regarding the allocation of resources."
Alternatives: "a notably challenging problem" or "an especially troubling matter".
Exact(1)
Tissue sampling can be a particularly problematic issue in IBC, since most cases present with no discrete mass and therefore accurate targeting of the area of breast for image-guided CNBs can be difficult [ 5, 6].
Similar(59)
One particularly problematic issue is that short accession numbers may be identical to medically important terms, such as "CD-34".
Leisure is a particularly problematic one in my view.
It doesn't seem a particularly problematic word.
Poor infrastructure remains a particularly problematic barrier to adopting digital payment systems.
A particularly problematic waste for local governments is the single-use plastic bag.
Heino Borchert is responsible for Oranienburg, a particularly problematic area.
The reign of his father, Edward II, was a particularly problematic period of English history.
This is a particularly problematic trend.
CVD with chronic pain appears to be a particularly problematic combination of the conditions.
This is particularly a problematic issue when assessing CRC progression and when comparing adenoma to cancer tissue.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com