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It's a particularly challenging question this year, since special elections have shown Democrats voting in large numbers.
As a graduate teaching assistant, I had the luxury of referring students to an experienced faculty member if I encountered a particularly challenging question.
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One particularly challenging question is whether private funds could effectively replace NIH's significant role in funding "basic" research.
Paediatric genomic research raises particularly challenging questions on whether and under what circumstances to return research results.
Diagnosing fibromyalgia is a particularly challenging challenge.
Determining how best to ask about Hispanic/Latino ethnicity was a particularly challenging issue in the development of the regulation, resulting in a question about Hispanic/Latino ethnicity followed by a separate question about race.
Increasing the extent of genetic variation available in rye breeding programs by utilization of exotic/primitive accessions is a particularly challenging task because, apart from being agriculturally poor-adapted, the materials in question are also heterozygous and self-incompatible.
A particularly challenging scenario is assessment of patients with communication impairments and we added a specific question on this.
Many of the most compelling questions involve contrasting ancestral patterns of plasticity with those in derived populations or species, a particularly challenging problem in the case of phenotypic plasticity.
Puberty is a particularly challenging time.
This is a particularly challenging bunch.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com