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The phrase "a particularly challenging issue" is correct and usable in written English.
You can use it when discussing a problem or topic that is notably difficult to address or resolve.
Example: "The team is currently facing a particularly challenging issue regarding the project's timeline and resource allocation."
Alternatives: "a notably difficult problem" or "an especially tough challenge."
Exact(7)
Resource management is a particularly challenging issue for vehicular cloud development.
Error detection is a particularly challenging issue in third-party error correction where different individuals are responsible for the original dictation and correcting the resulting text.
That makes 5G a particularly challenging issue for the company.
A particularly challenging issue is how increases in extreme precipitation regimes, which are characterized by larger but fewer individual precipitation events, will impact ecosystems.
Furthermore, control for confounding may be a particularly challenging issue in studies of screen time and mortality.
This is a particularly challenging issue in preterm birth research as the phenotype of preterm birth can be quite complex to define.
Similar(53)
More specifically, beyond the general findings discussed above, this study highlighted at least three particularly challenging issues for prioritarianism in priority setting as well as for priority setting more generally.
10 minutes at the start of each shift to talk about your service philosophy, to share letters from happy customers, to have someone on the team explain how they solved a particularly challenging customer service issue.
Diagnosing fibromyalgia is a particularly challenging challenge.
This week's votes will put Republicans in a particularly challenging spot, as they will spotlight the issue of whether millions of Americans get their tax refund checks.
Why is a child crying with frustration at a particularly challenging level on Candy Crush imply damaging neurological issues, but a child crying with frustration at having to memorise copious unfamiliar and unintuitive information an important aspect of their education?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com