The phrase "a particularly adverse effect" is correct and usable in written English.
It can be used when discussing negative consequences or impacts of a situation, action, or substance, emphasizing the severity of the effect.
Example: "The new policy has resulted in a particularly adverse effect on employee morale, leading to increased turnover rates."
Alternatives: "a notably negative impact" or "a significantly harmful effect."
Economic shocks, such as job loss, have a particularly adverse effect on the retirement savings of workers in low-income households.
Klein reviewed studies suggesting that the notion of a particularly adverse effect of visceral fat "may not be so true".
By impairing the development of adaptive immune responses needed for recovery, the apoptotic destruction of lymphocytes and dendritic cells could have a particularly adverse effect on disease outcome.
Women who had high Western pattern scores during adolescence and in adulthood had the greatest risk of T2DM compared with individuals with consistent low scores, suggesting that persistence of a Western-type dietary pattern into adulthood may have particularly adverse effects on T2DM risk, possibly through weight gain.
Hormones exerted particularly adverse effects in those initiating use subsequent to a diagnosis of benign breast disease, particularly long-term users (RR = 3.0, 95% CI 1.6-5.5 1.6-5.5
Due to their potential for ineffective and particularly adverse effects, NTIDs must be kept within an extremely narrow range, which may not be satisfied with current BE standards [ 12].
Evidence suggests that consuming high levels of fructose-containing beverages may have particularly adverse effects on selective deposition of ectopic and visceral fat, lipid metabolism, blood pressure, insulin sensitivity, and de novo lipogenesis, compared with glucose-sweetened beverages (142).
For instance, the much-emphasized 'double burden' of over-nutrition and under-nutrition worldwide has particularly adverse effects for children, low-income nations where western diets are taking hold, and for Inuit communities in the Arctic (e.g. Galloway et al. 2012; Huet et al. 2012; Prakash 2012; Kimani-Murage 2013).
Short-term experimental studies suggest that fructose, which is a constituent of both sucrose and high-fructose corn syrup in relatively equal parts, may exert particularly adverse metabolic effects compared with glucose.
To top that, news about the Zika virus spreading on the island is also having an adverse effect, particularly because it's keeping tourists away from visiting.
Some studies have indeed found evidence of such an adverse effect, particularly in boys and in children from low-SES families [ 34, 35], but other studies failed to find such an effect [ 36].
