Sentence examples for a particular transporter from inspiring English sources

Substrates are substances that are transported (by transporters) or catalyzed (by enzymes), while non-substrates are substances that were experimentally tested and found not to be substrates of a particular transporter or enzyme.

Differences sometimes reflect the fact that one database has a particular transporter family while the other does not.

The aim was to find a particular transporter that is specifically upregulated in pancreatic cancer versus normal pancreas that could serve as a target for the future development of a PDAC-selective functional imaging probe.

Recently, it has been shown that a particular bicarbonate transporter (B. anthracis Sterne loci BAS2712-14, ortoologous to Ames Ancestor GBAA2920-22) importantant for B. anthracis virulence [16].

This can be done, for example, by changing plasma protein binding [ 123, 124], inhibition of a particular efflux transporter [ 125], blocking particular receptors [ 126, 127], or by induction of a pathological state [ 113, 128] and enabling us to learn about the contribution of individual processes in CNS target site kinetics [ 17] and dynamics [ 129, 130].

Dextrins of length 3 to 5 are the preferred substrate of C. thermocellum[ 50], and this particular transporter is one of five involved in carbohydrate transport and the only one with a specificity for cellotriose [ 33].

Moreover, we assessed whether ABC transporters influence the growth inhibitory effects of these antibiotics by proliferation assays using Madin Darby canine kidney II (MDCKII) cells overexpressing the particular transporter.

A related question surrounds the "natural" substrates of particular transporters that transport pharmaceutical drugs, but this could not directly be answered from similarity considerations alone.

Evidence supporting an additional role for particular transporters, as predicted by this study on hCNT1, could ultimately help to explain this apparent redundancy in transporter expression.

In many cases, a shared scaffold helps cluster drugs and endogenites, and gives insight into enzymes (in particular transporters) that they both share.

Understanding the substrate/inhibitor profile of a particular amino acid transporter has a number of potential uses in pathophysiological conditions as amino acid transporters can be utilised to mediate uptake of substrates that will alter cellular function or as a mechanism to deprive cells of essential nutrients [35].