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Few in vitro cell assays can be used to represent a particular step of metastasis.
We discuss the molecular players that have been assigned a specific role in a particular step of this process and give a brief outlook on what these insights might tell us about mechanisms of short-term plasticity at classical synapses.
In their combats, plants use mechanisms such as antiviral RNA silencing that viruses fight against using silencing-repressors. Plants could also resist by mutating a host factor required by the virus to complete a particular step of its infectious cycle.
For instance, an instructional strategy guiding the solution-step loop may decide to work with a student on discovering and articulating a particular step of the solution or just skip the step depending on student's knowledge level with respect to the target domain and student's performance on the current problem so far.
The subset of mutation pairs used at a particular step of the approximation process was encoded in the binary weight matrix C( l), that is, <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0003284.e022.PNG" class= inline-graphic"/> if and only if the mutation pair (i, j) is used at step l.
One activity usually corresponded to one agenda point and referred to a concrete task for carrying out a particular step of the operational approach.
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Genentech has taken a particular step in terms of social responsibility.
Here, completion of a particular step in TTSS assembly triggers proteolytic processing of the TTSS and thereby changes substrate specificity.
This can be done either at the level of a particular step (corresponding to a defined EC number) in a pathway or by considering all the steps of a complete pathway.
A nucleotide was considered "engaged" if it formed a complementary base pairing in all predicted secondary structures of a particular step.
Taking this rather to extremes, Plowden argued that children should therefore be left to do their own thing: "Until a child is ready to take a particular step forward it is a waste of time to try to teach him to take it".Plowden scolded fuddy-duddy adults who could not accept this, and expected teachers to teach.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com