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Drugs marketed in the United States go through a rigorous F.D.A. approval process to prove that they are effective for a particular indication, with the potential risks balanced against the benefits.
Imaging is used in cancer clinical trials for various indications, and the study design needed to evaluate the imaging in a particular indication will vary.
While the link to a particular indication has been established in man, the mode-of-action (MOA) of the formulations is relatively unknown.
A mesh when implanted for a particular indication represents a foreign body which induces a foreign body reaction (FBR).
The choice of the optimal mesh for a particular indication with the highest functionality (hold shape) as well as minimized side effects remains difficult.
We were able to attribute AED prescription to a particular indication in up to 70% of our cohort, which permitted matching and possibly tighter adjustment.
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The UCI's head of off-road racing, Peter van den Abeele, said that the governing body had been testing a new detection system, not because it had any particular indication that fraud was going on, but because this seemed a good opportunity.
Within any particular indication, furthermore, no more than two trials evaluated clinically relevant endpoints of the same type.
A study like this would be akin to a Phase II pharmaceutical study (a controlled study to evaluate the effectiveness of a treatment or procedure for the particular indication in patients with the disease or condition under study and to determine the common short-term side effects and risks).
Certainly, more in-depth studies on the effects of BTA on pathologic scars and/or mature keloids are needed before a comparatively expensive therapy for this particular indication can be postulated.
However, "home visit" constitutes a unit of reimbursement independent of its particular indication.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com