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Discover LudwigThe phrase "a particular genome sequence" is correct and usable in written English.
It can be used when referring to a specific sequence of DNA or RNA that is of interest in a scientific context.
Example: "Researchers are studying a particular genome sequence to understand the genetic basis of the disease."
Alternatives: "a specific genome sequence" or "a certain genome sequence".
Exact(1)
Although some SNPs and/or indels may be omitted or ignored when using a particular genome sequence of a real isolate as a reference, these SNPs and/or indels would not be missed in comparative genomics, especially in phylogenetic research.
Similar(59)
Putative RAYT homologs can easily be found by a simple BLAST of conserved C-terminal part of any of known RAYTs against particular genome sequence.
Bacterial artificial chromosome (BAC) libraries have become an invaluable resource as a starting point for genomic research, and in particular genome sequencing, physical mapping, complex analysis of targeted genomic regions, and studies on gene structure and function [ 14– 14].
Constraint-based modeling has proven to be a successful paradigm in systems biology for describing and exploring the phenotype capacities for a variety of organisms based on its particular genome sequences and metabolic topology [11], [12], [13], [14], [15].
Consequently, a very efficient and viable strategy for obtaining the initial insight into the content and complexity of a particular genome involves sequencing the terminal regions of a representative number of BAC clones selected at random from this genomic library.
Evolutionary theory predicts an inverse relationship between evolutionary distance and sequence similarity (ED α 1/S or ED = μ/S where ED is evolutionary distance, μ is the mutation rate and S is percentage similarity) and it follows therefore that the sensitivity of a homology search of a particular genome increases if the sequences of closely related organisms are used in the search.
Papers announcing the sequencing of a particular genome or a high-throughput genome-scale analysis hardly do justice to all that can be inferred from the data presented in them.
In particular, a Neandertal genome sequence provides a catalog of changes that have become fixed or have risen to high frequency in modern humans during the last few hundred thousand years and should be informative for identifying genes affected by positive selection since humans diverged from Neandertals.
Since repeat regions may offer a particular challenge for genome sequence assembly in conifers, it is important to accurately detect and mask high and low complexity repeats.
In this sense full genome sequencing and assembly of different wild-type C. elegans strains [ 65] will be very helpful, in particular since a whole genome sequence of the Hawaiian strain has been recently released [ 66].
In particular, genome shotgun sequencing of such a large and repetitive genome seems currently impossible.
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