The wide range of NPs able to induce it, speaks against a particular chemical determinant being the trigger.
Previously, we have characterized a particular structural determinant that can trigger TDP-43 loss of function/interaction with hnRNP A2 and whose minimal region corresponds to residues 342 366 of the TDP-43 C-terminal tail (15– 15).
FISH-based detection of blaSHV-238/240, one of the genes coding for extended-spectrum β-lactamases (ESBL), is an example of a non-rRNA-based FISH protocol for detecting a particular resistance determinant using the probe 5′-GAC-CGG-AGC-TAG-CAA-GCG-3′ [ 105].
Rather, public health has a unique relationship of stewardship to one dimension of well-being, health, and to the particular determinants that have a special strategic significance for health.
According to this hypothesis, the time that a progenitor spends in G1 determines the final effect of a particular cell fate determinant, which could be equivalent (symmetric divisions) or distinct (asymmetric divisions) in the two daughter cells (Dehay and Kennedy, 2007, Gotz and Huttner, 2005, Salomoni and Calegari, 2010).
In particular, determinants of health workers' performance have not yet been fully understood.
Metagenome studies intrinsically do not allow drawing any reliable conclusions regarding the genomic context of particular determinants.
In order to limit the risk of bias, a wide range of methods were used to identify which determinants needed to be influenced, and the I-change model, which also takes into account the particular determinants, was applied.
It is the asymmetric localization of these particular determinants (in addition to other factors) to the basal side of the dividing neural progenitor cell that is largely thought to produce two daughter cells, each with a different fate.
