Sentence examples for a particular alteration from inspiring English sources

However, it is possible that a particular alteration, such as a single bp change, may not be identified with numerous displays and therefore, it is up to the examiner to determine the usefulness of 2DBGD for each particular case.

Summary plots, also denominated consensus plots, depicting the relative percentage of samples showing a particular alteration, were obtained by combining the required individual karyoscope maps using the same software.

To unify both types of data, and to adjust the MAF of mutations in genes with CNA, we introduce mutation cell frequency (MCF, defined as the fraction of tumor cells with a particular alteration) for quantification of genetic lesions ('Materials and methods', Figure 1 figure supplement 1).

Further investigations are required in order to elucidate whether the particular alteration has a founder effect within the Greek population.

Long bones are severely bowed, and altered structure of the growth plates lead to a particular structural alteration of the metaphyses and epiphyses described a "popcorn appearance".

This particular alteration of the BM possibly provides an altered niche that enables the central corneal basal epithelium to undergo de-differentiation and assume a phenotype resembling that of corneal stem/progenitor cells.

An alternative approach, which is effective even when the genetic alteration is difficult to reverse, is to isolate a drug that only kills cancer cells which harbour a particular genetic alteration, or which are compromised by other cancer-specific events.

HISA benefits approved by VA for use in a particular home alteration but unused by the beneficiary will remain available for future use.

The study built on knowledge developed over the previous decade showing that half of all patients with melanoma, the deadly skin cancer, possessed a particular genetic alteration in a gene called BRAF.

For example, if a study of a specific new drug failed to show a benefit in the patient population overall but did appear to work in a subset of patients, researchers can use Foundation Medicine's test to determine if there is a particular genetic alteration that predicts who is most likely to respond.

The drugs included in the trial have either been approved by the U.S. Food and Drug Administration FDAA) for another cancer indication or are still being tested in other clinical trials but have shown some effectiveness against tumors with a particular gene alteration(s).