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Another clue is a paradoxical finding about a hormone, adiponectin, made by fat cells.
Although PDZRN3 has a role in myoblasts differentiation, we observe a paradoxical finding during adipocyte differentiation.
This has always been a paradoxical finding given the substantial sequence conservation between these proteins [4].
These lesions contain activated Erk, a paradoxical finding considering that the patients are treated with an inhibitor of the pathway.
It is a paradoxical finding whose most likely implication is the lack of a protective effect of maintenance therapy in our MDD sample.
For example, a paradoxical finding is that the absence of estrogenic activity in the feed during pregnancy resulted in the "fetal estrogenization syndrome" and obesity during later adulthood in CD-1 mice (Ruhlen et al. 2008).
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This is a seemingly paradoxical finding, as H2O2 is a known inducer of the Nrf2 pathway that regulates HO-1 expression (Fourquet et al. 2010).
However, positive feedback that is merely praise also can reduce autonomous motivation [ 57], a seemingly paradoxical finding that can be understood as the consequences of the feedback in effect becoming an extrinsic (i.e., controlling) motivator.
If so, this could explain a seemingly paradoxical finding of ours (13) and others' (15), namely that GAD antibody titers are negatively associated with a family history of diabetes in patients with LADA.
Notably, an unexpected paradoxical finding was reported in anti-amyloid immunotherapeutic studies in AD [ 19, 43], showing a reduced volume in hippocampus, whole brain, and cortex.
This, at a first glance paradoxical finding, is in accordance with the results from other studies where the total antioxidant status was measured with the FRAP assay [ 32, 33].
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Justyna Jupowicz-Kozak
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