These results of Stone are still a paradigm for developments in the algebra of logic.
5– 8 VEGF-A, the first VEGF characterized, has served as a paradigm for the development of antiangiogenesis as a therapeutic strategy, including the clinical development of bevacizumab, a humanized monoclonal antibody targeting VEGF-A.
In the current issue, Wielscher et al. (2015) develop a four gene DNA methylation signature for the detection of lung cancer and its differentiation from other lung diseases with a high risk of cancer development, such as COPD and ILD, in retrospective cohorts and provide a paradigm for the development of DNA methylation-based diagnostic assays.
Yuthavong, Y. et al. Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target.
Service-Oriented Architecture (SOA) is a paradigm for software development based on the concept of service.
The approach serves as a paradigm for the development of general models for open-cathode active-feed DMFC systems.
It is an important discovery because the finding may provide a paradigm for the development of phosphatase inhibitors that enter cells and modify signal transduction.
The paper presents scientific experiments as a paradigm for the development of an integrated methodology with a purpose to restrain limitations, compound merits and produce a syncretism of complimentary venues for synthesis and optimisation.
Here we review the properties and biological activities of the recently discovered avian cathelicidins and their potential to be used as a paradigm for the development of anti-infectives.
We systematically investigated the dynamic characteristics of celluar and humoral immune responses, and explored the relevant molecular events in pigs vaccinated with UV-attenuated cercariae, which could provide a paradigm for the development of optimal vaccine formula for human use.
The outcome of the review, however, is clearly a result of political compromise rather than an effort to set a new paradigm for development policy.
