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In a landmark study of the effect of a one-time dose of the antibiotic streptomycin on the gut metabolome of mice, Antunes et al. showed that over 80% of the detectable metabolites in feces showed altered abundance compared with those in the non-treated communities.
S/P is a one-time dose.
Wounds were harvested upon complete wound closure (postoperative day 15) for histological examination and biomechanical testing of scar tissue.RESULTS: A one-time dose of 3.90 mM doxycycline (2 mg/mL) within 12 hours of injury was found to significantly reduce scar thickness by 24.8% (P < 0.0001) without compromising tensile strength.
A one-time dose of cash, cows, goats, or other assets and services made families healthier and better off for at least a year, researchers found.
A one-time dose given in the thigh, the vitamin K shot protects infants until 4-6 mofths of age, when they start consuming sources of the vitamin in solid food and when beneficial bacteria that produce vitamin K populate the intestines.
All annual flu shots are covered under Medicare Part B. Td/Tdap (tetanus, diphtheria, pertussis): A one-time dose of the Tdap vaccine, which covers tetanus, diphtheria and pertussis (whooping cough) is recommended to all adults.
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Today, there is a rather greater emphasis on developing drugs that eradicate these infectious organisms with a single, one-time dose than there is on experiments that focus on the basic science of the disease.
Rather than a high concentration, one-time dose of marketing, such as an Olympic campaign, our findings suggest that long-term brand-building, as well as developing a consumer centric point of sale, are the two critical points in convincing consumers to buy a certain brand or product.
We investigated the ability of a furosemide stress test (FST) (one-time dose of 1.0 or 1.5 mg/kg depending on prior furosemide-exposure) to predict the development of AKIN Stage-III in 2 cohorts of critically ill subjects with early AKI.
A one-time revaccination dose of PPV23 is recommended 5 years after the first dose for asplenic or immunocompromised persons.
Small amounts of potent ingredients can, in theory, mean far less skin irritation, as one might get with a one-time high dose of retinol.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com