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The metastatic niche provides a number of survival functions for DTCs.
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Mammalian cells express a number of survival genes that play the roles in inhibiting caspase activation, removing harmful oxygen radicals, defending mitochondrial function, and checking cell cycle.
The Kaplan-Meier estimator with a log-rank test for linear trend was used to examine the overall difference of survival functions stratified by the number of genotypes of interest.
A stochastic comparison result between two systems is also obtained using phase representations of survival functions.
The flight membranes of bats serve a number of physiological functions important for survival.
This early postnatal period is critical for development of independent survival; therefore, a number of LH functions appear to become active early.
NGF is a neurotrophic factor that regulates a number of vital functions of the neurons including survival, growth, proliferation, and differentiation [ 10].
The Growth factor Receptor Bound (Grb) adaptor proteins are a group of structurally similar proteins beginning to emerge as key players in a number of cellular functions including cell metabolism, cell survival and cell migration.
NOTCH1 signalling is involved in a number of biological functions, including regulation of self-renewal capacity, survival and promoting terminal differentiation.
The spliced form of XBP1 mRNA generates a transcription factor that codes for proteins that account for a number of functions that converge to cell survival and ER homeostasis, DNA repair, cell differentiation [30] and protection against oxidative stress [31].
PAK1 has been reported to have a number of functions (e.g. cell survival, motility, proliferation) and is implicated in transformation and tumour progression (Huynh et al., 2010).
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