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The phrase "a number of large" is correct and usable in written English.
It can be used when referring to multiple large items or quantities in a general context.
Example: "A number of large companies have decided to invest in renewable energy."
Alternatives: "several large" or "many large".
Exact(57)
& direcor of a number of large corporations.
A number of large agencies have graduate training programmes.
However, it is clear that a number of large retailers are experimenting with it.
He advises a number of large charitable trusts and is frequently quoted in the media.
"There's a pond and a number of large trees, which birds like".
There are also a number of large environmental consultancies, for example WS Atkins in the UK.
A number of large corporations have their headquarters in Rhode Island.
He executed a number of large landscape screens, all of which are now lost.
It shows the level of secrecy in a number of large financial centres increasing, not falling.
GENERAL MOTORS A number of large S.U.V.'s may suffer leaks of power steering fluid.
Sun also has a number of large campuses and an extensive research and development operation.
More suggestions(18)
a number of overwhelming
a number of vast
a number of considerable
a number of huge
a number of massive
a number of substantial
a prevalence of large
a number of major
a multitude of large
a number of broad
a number of significant
a number of wide
a number of tremendous
a number of enormous
a number of degrees
a number of broader
a number of sizeable
a number of large scale
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com