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So the statistic that sex workers in London suffer a mortality rate 12 times higher than average is not a noxious effect, nor is the trafficking from East to West of thousands of young girls a year to work in the sex industry?
Very specifically, in the case of the Microtox®test, the sensitivity of the luciferase complex to toxic elements must be considered as a near indicator of a noxious effect.
Soon after being available on the market, the first generation emulsions, made from soybean oil, were thought to have a noxious effect on the immune system, especially when given in great amounts.
However, some studies have proposed a noxious effect of SM application.
Postprandial glucose (PPG) has a noxious effect on the vascular endothelium, which is mainly mediated by oxidative stress.
Antibodies targeting plaques could even have a noxious effect by solubilizing fibrillar and innocuous Aβ [ 5, 32].
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Chemotherapy drugs used to treat cancer can be neurotoxic by either exerting a direct noxious effect on the brain or the peripheral nerves.
This protective function was not limited to H2O2 challenge but was also clear against 6-OHDA, a neurotoxin whose noxious effect reproduces what happens in the dopamine-selective environment of PD neurodegeneration.
"On the western shore of the Dead Sea, the Essenes have withdrawn to a sufficient distance to avoid its noxious effects—a solitary people, and extraordinary beyond all others in the whole world, who live without women and have renounced all commerce with Venus; and also without money, having the palms for their only companions.
Most patients who develop a noxious side effect think about it, decide to call the doctor (if they can get past the gatekeeper) or stop the medication.
The second noxious effect of activated microglia in PD was an increased production of reactive oxygen species, such as NO and superoxide.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com