Sentence examples for a novel underlying from inspiring English sources
In addition, the evidence that inactivation of MAD2 leads to suppression of MEK pathway in response to cisplatin suggests a novel underlying mechanism responsible for the MAD2-mediated cellular response to DNA damage.
In the present study, we showed that silencing of Twist1 is associated with ATP depletion, leading to AMPK-activated mTOR inhibition, highlighting a novel underlying mechanism of linking between the Twist1 and mTOR pathways.
Our findings demonstrate that key neuropathological features of FTD/ALS with GGGGCC repeat expansions can be recapitulated in iPSC-derived human neurons and also suggest that compromised autophagy function may represent a novel underlying pathogenic mechanism.
Our data also demonstrates that the finding provides a novel underlying mechanism of combination therapies via IL-18 and GM-CSF that promoted tumor antigen presentation and induced proliferation of tumor-specific T cells.
These data provide a novel underlying mechanism for the anticancer activity of simvastatin, which could have potential implications for the strategic use of statins in the management of cancer.
They discussed the cultural acceptance of gender around the new femininity from cultural and historical aspects through <Madame Freedom>, the original novel underlying the movie <Madame Freedom>.
Throughout the novel, underlying themes of mundane heroism and nuclear holocaust appear.
In these shared biological modules, novel underlying disease genes could be predicted from some known disease genes.
Some genetic and genomic approaches may facilitate the identification of biological risk markers and reveal novel underlying mechanisms.
These data revealed a novel mechanism underlying astrocyte-neuron interaction in disease.
Increasing the frequency of MDSCs by glucocorticoids might serve as a novel mechanism underlying the suppressive effect of glucocorticoids on various chronic inflammatory and autoimmune diseases.
