The phrase "a novel mode" is correct and usable in written English.
It can be used to describe a new or innovative method, approach, or way of doing something.
Example: "The researchers introduced a novel mode of transportation that significantly reduces travel time."
Alternatives: "an innovative method" or "a new approach".
& Stys, P. K. Axo-myelinic neurotransmission: a novel mode of cell signalling in the central nervous system.
Magill, D. J. et al. Localised genetic heterogeneity provides a novel mode of evolution in dsDNA phages.
Shiau, A. K. et al. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Bledsoe, R. K. et al. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.
Sodium glucose co-transporter 2 inhibition is a novel mode of treatment for type 2 diabetes mellitus (T2DM).
A 2.1 Å resolution crystal structure of the human RhoA GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.
Functional −1 PRF signals that seem to be regulated by miRNAs are also demonstrated in mRNAs encoding six other cytokine receptors, suggesting a novel mode through which immune responses may be fine-tuned in mammalian cells.
His sport in the South American jungle was blasting innocent melons to a pulp, and in Mexico City he tried out a novel mode of pest control, stringing up live mice and blowing their little heads off.
We identified the proto-oncogene DDHD2 as a target of miR-503 that requires pairing outside of the canonical 5' seed region of miR-503, representing a novel mode of miRNA-target pairing.
Given that endogenously generated ROS are also used as signaling molecules, our analysis suggests a novel mode of action to explain oxidative stress-induced pathological conditions and diseases.
"The discovery of this new antibiotic, from a new class with a novel mode of action, is very exciting.
