Sentence examples for a novel dosing from inspiring English sources

To evaluate the safety and acceptability of a novel dosing regimen of methotrexate to treat ectopic pregnancy.

Caroline Loew of PhRMA, the American drug industry's lobbying arm, argues that disclosing details such as an experimental compound's proper scientific name could tip-off rival researchers that a firm has found a novel dosing regimen or a new use for an old compound.

Detailed pharmacokinetic modeling led to the development of a novel dosing schedule designed to achieve target drug concentrations in vivo.

44 We have reported a novel dosing regimen for eptifibatide in patients undergoing elective PCI.

We conducted a randomized, placebo-controlled phase I study to assess the safety and tolerability of eltrombopag, utilizing a novel dosing schedule, to determine an optimal eltrombopag dose in patients with solid tumors receiving gemcitabine as monotherapy or combined with cisplatin or carboplatin.

In our trial, we chose a novel dosing regimen for AZA (100 mg/m/day for 5 days) which avoids the "weekend problem" while providing an overall dose of AZA (500 mg/m/cycle) that is very similar to the approved regimen (525 mg/m/cycle).

Accelerated BEP is a novel, dose-dense regimen that was tolerable for the majority of our patients.

Additionally, a novel dose schedule of 5-AZA-CdR for treatment in patients with cancer is suggested due to the myelosuppression induced by high doses [ 52].

The aim of this study was, therefore, to determine the toxicity and effectiveness, in terms of the response and survival of alternating BOP/BEP, a novel dose intense combination chemotherapy regimen, based on individual components with which there was already considerable experience.

The method of choice for defining this relationship is the use of a well-understood probe (or radioligand) which allows the quantification of target availability at baseline and following the administration of various doses of a novel drug.

If a novel drug formulation offers less frequent dosing or fewer side effects, these improvements may be enormously important to patients, possibly making a difference in determining whether or not a patient takes the medicine.