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The phrase "a noteworthy gap" is correct and usable in written English.
It can be used to describe a significant difference or absence in a particular context, such as research findings, data analysis, or comparisons.
Example: "The study revealed a noteworthy gap in the existing literature regarding the effects of climate change on local ecosystems."
Alternatives: "a significant disparity" or "an important difference".
Exact(2)
Google's Q3 earnings leaked today, and among the reported stats was a noteworthy gap in full-time employees between its Q2 and Q3 results.
In Africa and the Pacific, there is a noteworthy gap between the figures for total output and cited output.Figure 5 offers a comparison of the rates of production and of citation.
Similar(58)
This is an especially noteworthy gap in the knowledge base, given the calls to engage all students in research experiences and that research has suggested that different students may realize different outcomes from participating in research (e.g., AAAS, 2011; Thiry et al., 2012).
The predicted amino acid sequence of C05D2.3 contains one noteworthy gap: it is missing six amino acids from a highly conserved region found in all other PLP-dependent decarboxylases.
A noteworthy property of the alignment graph is that each genomic segment that is aligned without gaps in all pairwise alignments is represented as a single vertex in the graph.
He's a noteworthy person.
It was a noteworthy qualifier.
It's a noteworthy interview.
But Whedon adds a noteworthy fillip.
He was a noteworthy opponent of Pres.
However, Fig. 2 reveals a noteworthy detail.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com