The phrase "a notable shortcoming" is correct and usable in written English.
It can be used to highlight a significant flaw or deficiency in something, such as a product, service, or argument.
Example: "The report presented some valuable insights, but it also had a notable shortcoming in its lack of empirical data."
Alternatives: "a significant flaw" or "a major deficiency".
A notable shortcoming in the current research is the lack of systematic guidelines available to appropriately select model parameters.
A notable shortcoming (shared with heatmaps) is that the nature of the compounds in the dataset is not simultaneously well represented: it is only possible to show a few properties, through node color, size or superimposing numbers.
In particular, OCT is able to visualize flow profiles in planes that are orthogonal to a ciliated epithelial surface, a notable shortcoming in previously used imaging approaches.
(Innovation directly related to the healthcare provision) Lack of quantitative evidence was seen as a notable shortcoming not only for the sustainability and diffusion of the innovation but also for its initiation.
A notable shortcoming that we have identified regarding the ECDC and EMCDDA Guidance is a lack of attention to how gender and cultural issues should be taken into account in efforts to reach and assist the full array of PWID who need services.
These factors will clearly influence both haemoglobin levels and quality-of-life, and thus the inability to adjust for their effects is a notable study shortcoming.
The most notable shortcoming is the absence of a mechanism that allows users to add their own friends, so they can see what their buddies from high school are saying about the game.
Another notable shortcoming in the prior studies is the lack of a non-invasive method of joint injury to initiate PTOA.
The other notable shortcoming is that these things don't speak iTunes.
Critics cite continuing outsize budget deficits, driven by subsidies and state infrastructure spending, as one notable shortcoming.
Overall, we conclude that only a fraction of kown variation was captured, with notable shortcomings in detecting insertions and duplications in the 100-bp to 10-kb size range, and at repetitive DNA sequences.
