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The phrase "a notable difference between the two" is correct and usable in written English.
It can be used when discussing or comparing two items, concepts, or subjects to highlight a significant distinction.
Example: "There is a notable difference between the two approaches to problem-solving, which can affect the outcome of the project."
Alternatives: "a significant difference between the two" or "a marked difference between the two."
Exact(13)
Other experiments, notably at the Fermi National Accelerator facility in the US, have not definitively found a notable difference between the two kinds of decay of D-mesons.
A notable difference between the two results is that the Blinder-Oaxaca decomposition overestimates the unexplained part of the gap (the coefficient effect) and underestimates the explained part of the gap (the characteristic effect).
But Schaible clarifies that there is a notable difference between the two mechanisms at play here.
Seltzer water and club soda are very similar, but there is a notable difference between the two.
There's a notable difference between the two models, as you can see on the graph below, with an average difference of 2percentt and a maximum difference of 3.2percentt.
However, there is also a notable difference between the two concepts.
Similar(47)
A notable difference between the three families of PP2A holoenzymes is their distinct A subunit conformations.
Another notable difference between the two oxides is the role played by an oxygen vacancy in the movement of a cation vacancy.
Still, I've found several, five to be exact, notable difference between the two.
Perhaps the most notable difference between the two cities is found in the household income characteristics.
She said the most notable difference between the two characters was the style of music, rather than physical appearance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com