The phrase "a notable constraint" is correct and usable in written English.
It can be used when discussing limitations or restrictions that are significant or worthy of attention in a particular context.
Example: "The project faced a notable constraint in terms of budget, which affected the overall timeline."
Alternatives: "a significant limitation" or "an important restriction".
All these processes must share the limited space in the membrane; thus it represents a notable constraint on cellular functions.
A notable constraint to their market expansion has been the lack of involvement of large scale retailers, unlike what has been occurring in northern European countries, where supermarket chains drive the rapid growth in sales of organics.
A notable constraint in the use of iPSCs for studies of basic and disease mechanisms regards the time frame of in vitro experiments and the time required for the onset of psychiatric and neurological diseases.
David brings up a great point, which is that when developing a game under notable constraints, the kind of limitations that massive studios aren't usually required to grapple with, concessions do in fact happen.
They have done so despite notable constraints on their political activities, including limits on their lobbying and partisan electioneering, limited organizational resources, and dependence on government funding.
The most notable constraints imposed upon vehicle trajectories in traffic video surveillance are summarized below.
But teasing out the ramifications of the falsity of (d) reveals some notable constraints upon the sum theorist.
There are some notable constraints with this pesticide data set.
As a notable exception we show that the consistency problem for the AtMost-NValue constraint admits a polynomial kernel consisting of a quadratic number of variables and domain values.
Golemetry, cut loose from the traditional constraints of mud, dust or sand, is also a notable branch of thaumaturgy in China Miéville's rebellious, seething New Crobuzon and its environs.
In summary, the increased scope of modeled genes in iJL1678-ME caused a notable change in protein expression levels, and these shifts can be directly attributed to model updates and constraints derived from biochemical knowledge available in literature.
