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We made the assumption that genes with no alteration in expression level in DpDf plants relative to normal siblings will exhibit a normalized distribution of ratios centered at the value of 1.
The frequency of antigen specific, p-MHC reactive T cells does not follow a normal istribution [19] and for this reason all subsequent statistical analysis on memory cells was performed on a normalized distribution of log transformed data.
To correlate retroviral integration and gene activity, average expression values from the three microarrays were divided into four classes, i.e., absent, low (below the 25th percentile in a normalized distribution), intermediate (between the 25th and the 75th percentile) and high (above the 75th percentile).
This log transformation was performed to obtain a normalized distribution of the data.
HDL and non-HDL values were log2 transformed resulting in a normalized distribution for each set of values.
Thus, a normalized distribution density (number of mimic sites/1000 nt) was generated for each region category.
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a The normalized distribution of total points.
As above, we logarithmically transformed the biomarker variables to create a more normalized distribution.
To determine the distance between any two promoters, the average H3K9ac signal strength in each bin was determined and a cumulative normalized distribution across all bins reflecting the strand orientation of the promoter was calculated.
First, we do not typically know the statistical properties of the normalized count data and assuming a normal distribution for normalized count data might in some cases corrupt the analysis [ 26, 27].
For a normal distribution of normalized expression signals for a certain gene, τ ≈ 2.64.
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