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But federal law also allows the FDA to incentivize drug research and development by granting marketing exclusivity to manufacturers who demonstrate a new use for a drug, or even a new dosing regime.
For instance, Nguyen et al. have developed a new dosing regimen for busulfan in infants, children and adolescents through the use of population PK model.
The aim of the present study was to determine the pharmacokinetic and pharmacodynamic properties of danaparoid in patients with suspected HIT treated with CVVH, using a new dosing scheme based on a mathematical model.
In the event of DLT, dosing was to be held until recovery to at least Grade 1 toxicity and a new dosing cycle for that patient was to be initiated at the investigator's discretion at 50% of the previous dose.
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Investors, already nervous about the impact of tighter credit and a worsening economy on showroom traffic, were given a new dose of gloomy news on Thursday from the research firm J. D. Power & Associates.
To the Editor: Re "Sanford Case a New Dose of Bad News for Republicans" (news article, June 25): Republicans are very good at taking complex issues and simplifying them — to the point of absurdity — to black and white caricatures.
Regular customers come in for a new dose of abuse.
Still others began proposing that a new dose of irony might be in order.
Then try this Danish-built monster, which sounds like a new dose freshly concocted in some eastern European basement.
But the idea received a new dose of support when the Business Roundtable listed a one-year exemption from payroll taxes on the first $10,000 a person earns.
But now the troika's raid on their accounts — Russians call it a theft — has given Russians a new dose of anti-Western passion and paranoia.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com