To this end, we evaluated changes in lethal time for 50% of pharate larvae (Lt50) from eggs exposed to −2 °C in two subsequent generations that used a new dose-response test design.
In new dose response experiments suggested by the reviewer, expression of physiologically relevant levels of mutant SPOP led to increased sensitivity to olaparib compared to control cells.
We conclude that the novel PDC module studied here exhibits new dose-response behaviour.
With the new dose-response functions presented herein, the application of QMRA to pertussis, GAS pharyngitis, and viruses causing the common cold can begin.
This allowed them to derive new dose-response relationships relating the observed health response to the total internal dose of the metabolites at the target tissue (bone marrow in this case), rather than to the external environmental concentrations (doses) of the chemicals in the mixture.
Regular customers come in for a new dose of abuse.
As a result, seven new exponential dose response models for human-relevant species of MAC with endpoints of lung lesions, death, disseminated infection, liver infection, and lymph node lesions are proposed.
In classical toxicology packages for a new chemical, toxicokinetic studies, dose response patterns and/or knowledge of the structure of the test substance facilitates interpretation of apparent sex differences in metabolism.
We have this both as calculated parameters from a full dose response curve, and as a full dose response curve.
There was a clear dose response.
