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We had hoped that using two pre-erythrocytic antigens would improve protection, but it appears that a negative interaction is occurring when animals are exposed to these two antigens.
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Firstly, the estimates for the main effects of the other interventions (analgesia, dosing, steam) suggested no effect of these interventions (therefore a ceiling effect resulting in a negative interaction was unlikely).
Whether their negative interaction is due to TV editing or truly a sign of relationship trouble, I'll never know.
The borderline between positive and negative interaction is, unhappily, easily crossed.
The reason for this supposed negative interaction is not clear.
This negative interaction is also of unique character.
This potentially negative interaction is prevented in K217A, resulting in increased DNA binding and extension activities.
This negative interaction is equivalent to robustness, and mutations will have initially small (or nearly neutral) effects.
In addition, a significant negative interaction was found with BMI at baseline.
A marginal negative interaction was also found between PSS and log patella lead (p-interaction = 0.06) (Table 2).
The negative interaction was between Ma cytoplasm and one of the two Sp alleles.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com