Exact(6)
In the first stage, there was a positive agreement of 75% and a negative agreement of 73% for nurses finding one or more triggers.
In the second stage, physicians showed a positive agreement of 61% and a negative agreement of 84% for determination of AEs.
In addition, when this criterion was applied to FPX patients, 7 of the 8 patients with VTE met the criterion, and there was a negative agreement rate of 48/49.
In addition, when this criterion was applied to patients in the FPX group, 7 of the 8 with VTE met the criterion and there was a negative agreement rate of 98.0% (48/49).
As we observed the paradox of a low kappa value and relatively high observed proportion of agreement, which is the result of the imbalance in the distribution of the marginal totals in the cross-table, we calculated a positive agreement index and a negative agreement index in addition to Cohen's kappa (see Additional file 1 for calculations) [ 29, 30].
The second-generation assay has improved sensitivity to detect anti-JCV antibodies compared with the first-generation STRATIFY JCV assay (limit of detection = 60ng/ml and 350ng/ml, respectively) and was shown by Focus Diagnostics to have positive agreement of >97% and a negative agreement of >90% when compared with the first-generation assay.
Similar(54)
Positive agreement was calculated by the formula p pos = (2a)/(N + a - d) and negative agreement by p neg = (2d)/(N – a + d), where N is the number tested, a is the number positive by both tests, and d is the number negative by both tests [ 19].
For AD samples we achieved 100% positive agreement and for NDC samples a 92% negative agreement (Fig. 3d).
The recommendations that reached a high level of negative agreement (mean score between 1 and 3) were considered as rejected.
ICU: intensive care unit; ICUAW: ICU-acquired weakness; MRC Medical Research Council MMTmanualnual muscle testing; IQR: interquartile range; p-neg: proportion of negative agreement; p-pos: proportion of positive agreement.
Figure 1 illustrates the basis for calculating positive and negative agreement using a standard 2 × 2 table.
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