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The phrase "a need to substitute" is correct and usable in written English.
It can be used when discussing the necessity or requirement to replace something with another option or alternative.
Example: "In this recipe, there is a need to substitute regular flour with gluten-free flour for those with dietary restrictions."
Alternatives: "a requirement to replace" or "a necessity to exchange".
Exact(3)
There is a need to substitute the single state sequence designer with a multi-stable sequence design algorithm to take into account the multi-stable characteristics of the molecules.
On the other hand ordinary sand for filter media is costly because of construction-expansion in the country, not available readily and not efficient in the removal of hazardous pollutants by adsorption hence there is a need to substitute pumice and scoria instead of sand filtration.
For some, I imagine watching it fulfils a need to substitute what is perceived of as a "lack"; it's the desire to intervene, to meddle and project your desires into a scene where you are not necessarily needed nor wanted.
Similar(57)
He argues that we need to substitute a "living wage" of $8 an hour for the current minimum wage of $5.15.
What Maher should have done was interview atheists themselves, the likes of Christopher Hitchens and Richard Dawkins, and investigate the ethical burden that atheism has to shoulder, the need to substitute a rational morality in place of superstition.
However, because we are in a relative survival setting, we first need to substitute the estimates of the all-cause survival, S t) and cancer-specific hazard, h c (t), with their relative survival counterparts.
And when a recipe calls for shallots, there will be no need to substitute or omit.
Gradually there was no need to substitute ingredients because you could find a shop that catered to the most peculiar Ghanaian tastes anywhere in the world.
Growers might need to substitute insect pollination with alternatives for a number of reasons.
If you need to substitute dried herbs for fresh herbs in a recipe, remember that dried herbs are more potent.
You only need to substitute the amaranth flour for regular flour when making a gluten free cookie.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com