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However, there is a need for considerable caution here.
In this paper we review and discuss HRA methodologies, arguing that there is a need for considerable further research and development before they meet the needs of modern risk and reliability analyses and are able to provide managers with the guidance they need to manage complex systems safely.
DOI: http://dx.doi.org/10.7554/eLife.00467.008 The rapid kinetics of gain changes at both light onset and offset indicate a need for considerable integration of signals across rods.
Instead, there is a need for considerable funding, persistence, and continuity of effort to bring gene therapy into rheumatologic clinical practice.
It is clear that there is a need for considerable additional research and examination of the mechanisms of action of mindful parenting interventions.
The low overall pneumococcal polysaccharide vaccination rate of 45% however, (69% among those 65 years and older) indicates a need for considerable work if rates are to reach Healthy People 2010 goals of 90% [ 3].
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A 'huge inequality' compared with younger age groups was identified in terms of access to publically funded palliative health services and a need for 'considerable work' was identified 'to minimise the distress and maximise dignity for older people [and their families] at the end of their lives' [ 6].
There is a need for treatment services for a considerable minority of refugees even many years after the resettlement.
Bacterial taxonomy will never reach a fixed state, and the availability of genome sequences has increased the need for considerable reshuffling of groups.
Further, these fractures are typically associated with the need for considerable subsequent medical care, as they are accompanied by a much greater risk hospitalization in the subsequent year than experienced by THR recipients who did not have hip fracture.
These findings suggest the need for considerable efforts to improve PA connectivity globally.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com