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More than anything else, "Black Girl in Paris" is the story of a quest, each station providing a necessary trial on Eden's road to encounter her own personal wizard, the quintessential expat, James Baldwin.
Unlike some more seasoned big-name bands that the Seaport is able to attract, many of whom consider playing a free show to a family crowd a necessary trial of touring, Avi Buffalo seemed genuinely grateful to play as headliners to such a large audience.
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The authors of the RIAT proposal are confident that the necessary trial information can be obtained from clinical study reports.
But in spite of all this, I would argue that what we're seeing isn't a bubble per se, but rather a natural and very necessary trial-and-error process, where everyone -- entrepreneurs, fashion industry executives, investors -- is learning what works and what doesn't.
Preclinical animal research is a necessary adjunct to clinical trials as we seek to improve our mechanistic understanding of the pathophysiology of sepsis and the consequent effects of volume resuscitation.
Others see the trial as a necessary housecleaning by lawmakers of a judicial system that got too chummy with old-boy connections and too sloppy with ethical practices.
But if the trial is a necessary part of American life -- one of a series of private tragedies that take on public proportions and feed the need for national spectacle -- then the media have found a way to make it reliable entertainment.
The present feasibility trial represents a necessary step along that path.
Studies such as this would be a necessary prerequisite to any randomized trial comparing patient care delivered by different health worker cadres.
Given the challenges of recruiting participants and implementing interventions in a population with a high burden of illness, the success of our pilot was a necessary precursor to a principal trial that examines patient-relevant clinical outcomes.
While the decision to decrease the dose in the present breast cancer trial was a necessary and appropriate action to preclude potential toxicity, the magnitude of the reduction for a breast cancer population may have been too large.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com