Whole-animal toxicologic studies cannot yield the necessary throughput in a cost-effective fashion, leading to a critical need for a faster and more cost-effective toxicologic evaluation of xenobiotics.
Traditional methods of enriching for (or "capturing") specific genomic regions, such as standard PCR, lack the necessary throughput to provide an efficient front-end input strategy for 2nd generation sequencing platforms.
Through integration of biological and engineering principles, the CometChip provides the necessary throughput and sensitivity for a wide variety of applications in epidemiological studies, in the clinic and in drug development.
All of the components must work together seamlessly to ensure the necessary throughput.
The use of scalable parallelism to obtain chips with small areas for DVB-S2 has been proposed for technologies ranging from 0.13 µ m down to 65 nm [5 7, 15, 16] based on the processing of sub-sets of the Tanner graph, which guarantee the minimum necessary throughput of 90 Mbps required by the standard [8].
In addition to having the necessary throughput of patients to achieve the required recruitment rate of at-risk children (as defined by SIGN / BSPD guidelines [ 10, 11]), a schools-based setting will facilitate control over retention and follow-up.
This performance is a necessary condition for high-throughput structural classifications of complexes in whole-cell tomograms.
This is a necessary step for high-throughput differential expression studies at the transcript level, a direction we are planning to explore in future work.
Y. Zeng, A. Chaintreau, D. Towsley, and C. Xia, A Necessary and Sufficient Condition for Throughput Scalability of Fork and Join Networks with Blocking in Proceedings of ACM SIGMETRICS, June 2016.
Proposition 2 states that queue stability holds provably only for a part of the capacity region i.e., for ε c satisfying ε c λ i c ≥ ( ρ c − 1 ), ∀ c, i ∈ S ( c ) and not for ε c >0, ∀ c which is a necessary and sufficient condition for throughput optimality [27].
With the structure determination pipeline improving and novel protein structures increasing every year, scanning for function in a high-throughput fashion will become a necessary enterprise.
