The phrase "a necessary determinant" is correct and usable in written English.
It can be used when discussing factors that are essential in determining an outcome or result in various contexts, such as scientific, economic, or decision-making discussions.
Example: "In the study of climate change, carbon emissions are a necessary determinant of global temperature rise."
Alternatives: "an essential factor" or "a crucial element".
Instead, it appears that the high affinity binding to human receptors is a common factor shared by H2 HA with that of other human-adapted virus subtypes (H1 and H3) [21], [21] and therefore this property appears to be a necessary determinant for efficient human adaptation and transmission.
This led to the conclusion that tumour response in mCRC is not a necessary determinant of therapeutic benefit.
Together, these data show that mesenchymal FGFR signaling is a necessary determinant of cochlear length and sensory progenitor proliferation, but not for cochlear pattern formation or differentiation.
This demonstrates that whereas presence of the cluster is invariantly linked to use of APS as substrate, its absence is not a necessary determinant of PAPR.
We have reworded the paragraph to state that mesenchymal FGFR signaling is a necessary determinant of cochlear length and sensory progenitor proliferation, but not for cochlear pattern formation or differentiation.
From our study, we determined that both the intensity of the IHC staining of pAkt and the percentage of tumor cells stained with pAkt were necessary determinants for the scoring system.
The polyvalent vaccines, such as autologous whole-cell vaccines represented by PDT vaccines, secure greater coverage of potential/diverse tumour antigens (even if most of them are unknown) and include the necessary determinants for helper T cells (Copier and Dalgleish, 2006; Emens, 2006).
Awareness and interest in cancer screening is a necessary, but insufficient, determinant of screening behaviour.
CONCLUSION: Knowledge of HF and its management is a necessary though not sufficient determinant of HF self-care.
Our data underline the importance of HPA axis dysregulation for treatment outcome in major depression, although restoration of HPA system dysfunction seems to be neither a necessary nor a sufficient determinant for acute treatment response.
In contrast, genetic relatedness appeared to be neither a necessary nor a sufficient determinant of male caretaking behavior.
