Consequently, a new natural locus of infection may emerge.
To replace the ccpA promoter by a tetracycline-inducible promoter at the natural locus on the chromosome, the integration vector pWH849 was constructed as follows.
Other physical theories have gone beyond the neural and placed the natural locus of consciousness at a far more fundamental level, in particular at the micro-physical level of quantum phenomena.
However, in this report, an artificially introduced genomic locus was targeted; this study might therefore not represent a proof of concept for the stability of targeted DNA methylation at a natural genomic locus.
It is argued that the natural locus of 'style' in mathematics falls between the 'local' and the 'methodological' styles described by historians and philosophers of science.
The LCR included four distal DHSs that were required for perforin expression from its natural locus, and their engineered deletion from the PRF1 BAC transgene abolished LCR function and led to rapid gene silencing.
In its natural locus, two genes flank the TCRα LCR, TCRα (upstream) and Dad1 (downstream).
Chromatin from wild-type and hog1Δ cells expressing functional epitope-tagged Rsc1 and Rsc9 from their natural locus was immunoprecipitated and analysed by PCR.
Chromatin from wild-type and rsc9 ts cells expressing functional epitope-tagged Hog1 from their natural locus was immunoprecipitated and analysed by PCR.
If it can efficiently cut this sequence in organisms with one transgene and one natural locus, reliably induce the cell to copy the transgene, and avoid being too costly to the organism, it will spread through susceptible wild populations.
