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In addition, broadly expressed protein-coding genes are more conserved than those with a narrow expression profile [ 31].
As our knowledge of cellular proteins manipulated by HIV-1 expands, we expect that more proteins will be discovered that exhibit similar characteristics to Mov10 these being a narrow expression window in which HIV-1 is capable of reproducing.
This poses no problem at the low expression end, but at the high expressions the density of genes within a narrow expression interval is small and a certain number of genes (probe sets) must be excluded.
Of eudicot MADS box genes, C and B function genes generally show a narrow expression pattern, which directly reflects their function in carpel, stamen, and petal development, respectively [ 27, 53, 54].
The combination of the effect of the transgene with the range of selection generated by the antibiotic resistance marker can produce a narrow expression range that can mimic the physiological function range of expression.
For D. melanogaster and Mus musculus, it has been shown that sex-biased genes showing tissue-specific gene expression in reproductive tissues, and thus having a narrow expression profile within the organism, show faster rates of evolution than unbiased genes with tissue-specific expression or those with broader expression profiles (Meisel 2011).
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Interestingly, the more slowly evolving brain-related genes have wider expression while the rapidly evolving immune-related genes have a narrower expression pattern.
On either side of the podium were vertical banners with images of Moin — a gray-haired man with a narrow face and an expression of kindly intelligence.
As already mentioned, known micropeptides have a very narrow expression window [ 2, 5].
Y8b was expressed in all eleven tissues while the other four receptors showed a more narrow expression pattern.
The mRNA prototype designed in this study provides a very narrow expression window of transposase, which allows high efficiency transposition with no cytotoxicity.
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