The phrase "a multitude of alterations" is correct and usable in written English.
It can be used when referring to a large number of changes or modifications made to something.
Example: "The project underwent a multitude of alterations before the final version was approved."
Alternatives: "a variety of changes" or "numerous modifications".
Tumorigenesis is characterized by the accumulation of a multitude of alterations.
Gene expression profiling and genome-wide sequencing of human breast tumors has revealed a multitude of alterations [ 31- 33].
In addition, it has been suggested that during transformation PML RAR α induces a multitude of alterations in the chromatin architecture.
Finally, a multitude of alterations involving the apoptotic signaling pathways downstream the microtubule complex, as well as aberrant expression of microRNA, have been also found in resistant tumors.
Molecular imaging helps individualize patient treatment Through growing evidence from genetic profiling it is understood that cancer is not a single homogeneous disease, but that it is represented by a multitude of genetic alterations and changes at the cellular level.
Tumorigenesis is a multistep process characterised by a multitude of genetic and epigenetic alterations.
Rapid generation of NO and ROS following pathogen or elicitor challenge mediates a multitude of metabolic and transcriptional alterations including Programmed Cell Death (PCD).
See related research article by Crabb et al., Breast cancer, like many other types of cancer, is a complex heterogeneous disease controlled by a multitude of genetic and epigenetic alterations.
However, a large group of STS, e.g. MFH/UPS, leiomyosarcoma, and dedifferentiated/pleomorphic liposarcoma, lack known specific recurrent alterations and are characterized by a multitude of rearrangements, amplifications, deletions, and somatic alterations, including mutations in TP53, deletions of RB1 and CDKN2A, and amplifications of MDM2 and CDK4 [ 2, 3].
ADP was chosen as primary endpoint because there is a multitude of studies that have linked alterations in the ADP value associated with antithrombotic therapy with clinical events [ 9].
Functional studies show alterations in a multitude of brain regions, although being able to detect altered engagement likely depends on the tasks employed.
