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Trunnion or taper corrosion may be a multifactorial process, involving implant design, surgical technique, and patient characteristics.
β-Cell demise is a multifactorial process involving many stressors.
Chronic pain is well documented to be a multifactorial process involving physiologic and psychosocial variables.
Intervertebral disc (IVD) degeneration is considered to be a multifactorial process involving mechanical, genetic, systemic, and biological factors.
The pathogenesis of acne vulgaris is a multifactorial process, involving follicular hyperkeratinization and obstruction, increased sebum production, Propionibacterium acnes colonization, and inflammation.
This indicates that infection by these pathogens is a multifactorial process involving adaptation to particular conditions in target tissues and the human immune system, factors that should be considered during prevention and treatment of invasive mycosis.
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It is recognized that the pathophysiology of TBI is a multifactorial process involved in a complex and interwoven series of pathologic process following the onset of insult, such as increased extracellular glutamate concentrations, increased intracellular Ca2+, free radical overproduction and exacerbated inflammatory response.
At the outset, it could be postulated that the flux of a nanoencapsulated drug across MN-treated skin is a complex multifactorial process involving possible in-skin transport of the nanocarrier and the released drug through MN-created aqueous filled microchannels and deeper skin layers.
This is a complex, multifactorial process involving cartilage catabolism and anabolism, as well as changes in other tissues in the joints, such as the synovium, subchondral bone, and tendons.
The pathophysiology of chemotherapy-induced nausea and vomiting (CINV) is known to be a complex multifactorial process involving numerous neurotransmitters and receptors [ 1].
Hepatocarcinogenesis is a slow multistep and multifactorial process involving a progressive accumulation of changes at gene and protein level [ 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com