Sentence examples for a much lower efficacy from inspiring English sources

4′-OH-BDE-49 had an EC50 similar to that of DE-71 but a much lower efficacy; its maximal effect did not even reach the EC50 for E2.

Although we observed a much lower efficacy of treatment with PVPI than with mupi/CHX in eradicating MRSA occurrence, patients who received the two treatments differed considerably in terms of their risk of failure.

Consistent with this argument are results from the classic studies of Eagle et al. [ 39], in which mammalian cell lines in culture were shown to require approx. 0.3 μM inositol for growth, and this requirement could be fully substituted for by inositol monophosphates, or, with a much lower efficacy, by 1 μM Ins P6.

Many of these differences are explained by correcting for the high agonist efficacy of GABA at most αβγ receptors vs. much lower efficacy at αβδ receptors.

Furthermore, the bovine TAAR3 did not show any detectable activity and even the rat TAAR3, which is 95.6% identical to the mouse TAAR3 protein, exhibited much lower efficacy and potency to both agonists (Figures 4A, B).

The implementation of the same intervention in high transmission regions (parasite prevalence above 80%) (Figure 5B,D), indicates much lower efficacy in protecting against clinical episodes (blue line in panel B), but significant rebound in the age range under treatment (red line in panel B).

However, when tested in efficacy trials in Africa and Asia, these two vaccines showed much lower efficacy [ 38, 39].

Two other canonical site types, each associated with weaker preferential conservation and much lower efficacy (Friedman et al., 2009), are the 6mer (position 2 7 match [ Lewis et al., 2005]) and offset-6mer (position 3 8 match [ Friedman et al., 2009]).

Cells seeded on bovine cancellous bone demonstrated a much lower seeding efficacy and proliferative activity in comparison to cells seeded on β-TCP [ 42].

Through the development of a communication tool (a "balance sheet" summarizing published evidence on benefits and possible adverse effects of vaccination) to enable communities to balance costs and benefits of measles vaccination, Ledogar et al [ 13] uncovered a much lower vaccine efficacy rate in Lasbela, Pakistan, than expected.

This is in an excellent agreement with our data in the tail-flick analgesia test and recent work, which showed that EM2 has a much lower operational efficacy for G-protein mediated responses than DAMGO at native mu-opioid receptors in mature neurons [ 40].