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This was caused by 1) a much lower baseline forest area loss rate in general for the reduction in the North (−1.76%), compared to −6.64% in the West on average; and 2) a much higher forest carbon density and growth rate in the Pacific Northwest states and northern California[29, 30] where unprotected forestlands were concentrated (Figure 1).
However sanitation was starting from a much lower baseline (54%) than water (76%).
Recording of both blood pressure and cholesterol concentration improved with age, albeit from a much lower baseline for cholesterol.
Conversely, in European individuals, for whom we observed a much lower baseline expression, these variants may result in a larger relative effect that is sufficient to influence disease risk.
Similarly, a modest salt reduction of 50 mmol/24 h (from a much lower baseline than in our participants: an average of 177 mmol/24 h) resulted in 7/3 mm Hg drop in BP in a randomised trial in older people.
Figure 2 shows that emergency admission rates for the acute group of ACS conditions increased by 44% over the decade (p<0.0001 based on quarterly trends) while rates for vaccine preventable ACS conditions increased by 136% (p<0.0001), although from a much lower baseline.
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The much lower baseline expression of ABCA1 in the LRP1-deficient SMCs further suggested, that an endogenous LXR antagonist may be responsible for this nearly complete transcriptional repression.
Two major differences between the studies were the much lower baseline PhS in our study compared to the CAPS study (24.2 versus 43.4).
The results in the preference groups were consistent with the randomised comparison: scores after surgery in those who preferred surgery were somewhat higher than in those who preferred medical treatment, despite starting from much lower baseline levels.
Perhaps PI5P is produced via different routes in stimulated and unstimulated cells, or perhaps any decrease in PI5P is more difficult to measure against the much lower baseline in unstimulated cells.
We have found significantly elevated levels of circulating sPLA2 in Tg197 mice at 8 weeks of age as compared with the much lower baseline levels detected at 4 weeks of age.
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