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The phrase "a much less effective" is correct and usable in written English.
It can be used when comparing the effectiveness of two or more things, indicating that one is significantly inferior in effectiveness to another.
Example: "The new marketing strategy proved to be a much less effective approach than the previous one."
Alternatives: "far less effective" or "significantly less effective".
Exact(19)
Insulin was a much less effective inhibitor when HS was present, although there were modest effects on the time required to complete amyloid formation, and the effects of insulin were dose-dependent.
But Congress, lacking the presidential bullhorn, is a much less effective policymaking instrument than the White House, as Mr Gingrich eventually discovered.
If you can't convert the credit into something else of value in the world (gold, a dollar, a stock, a car), then it is a much less effective currency.
Even if, as has been widely discussed, the traditional 30-second spot has devolved into a much less effective way to sell goods and services, Mr. Berger said, "so what?" "The great agencies don't say, The 30-second commercial is dead, so we're dead.
Such a complex is a much less effective O2 carrier due to its higher affinity for autoxidation.
The better-managed company, with a much less effective ad campaign and a more effective portable power tool, won out.
Similar(40)
If there aren't any obvious physical effects, or if those effects don't show up while the disease is contagious, a quarantine is much less effective.
Although exact synchrony was not required to elicit aggressive responses from resident males, some degree of overlap between the two signal components was necessary; signals with temporal delays that did not include an overlap were much less effective.
It's a device that becomes much less effective the more it's used.
Calling him a racist will be much less effective than appealing to his principles: if you're so keen on the free movement of capital, why is the free movement of labour not also a liberty you should be championing?
"The most comprehensive study into tackling obesity, from the McKinsey Global Institute 2014 report and Public Health England, found that a tax would be much less effective than reducing portion sizes and reformulating products.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com